Procedure

The TIVUS™ System was developed to perform safe, reliable and highly reproducible transluminal renal nerve ablation using non-focused ultrasound technology.

The TIVUS system consists of the TIVUS™ catheter and the TIVUS™ control console. Ultrasound waves are transmitted from the tip of the TIVUS™ catheter through the arterial wall to ablate the surrounding renal nerves. Renal nerve ablation "resets" the body sympathetic tone/drive and results in BP reduction. The TIVUS™ console enables the interventionalist to control the treatment parameters (e.g. treatment intensity and duration).
The procedure is short (less than 10 minutes). Using routine renal catheterization techniques, the TIVUS™ catheter is advanced into the renal artery, led “over the wire” by a standard 0.014" guide wire. The catheter is positioned freely in the artery lumen, as the ultrasonic transducer requires no direct contact with the vessel wall. Ultrasonic energy is then applied at controlled parameters to induce thermal ablation of nerves. Nerves in the circumference of the artery are progressively treated by catheter rotation. The nerve ablation is carried out in several well-spaced and self-contained locations along the artery. Then after, the TIVUS™ catheter is retracted and advanced into the contralateral renal artery, where the procedure is repeated.

In summary, the unique TIVUS™ technology is used for effectively reducing BP, concomitantly with protecting the integrity of the arterial wall and reducing the risk of stenosis.